Pharmaceutics

Principle, Construction, and Working of Hammer Mill and Ball Mill Hammer Mill A hammer mill is a machine that is commonly used in the pharmaceutical industry to reduce the particle size of active ingredients and excipients. Diagram of Hammer Mill Principle of Hammer Mill The hammer mill operates on the principle of impact grinding, where …

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Tablet defects Tablet defects related to the tabletting process Capping and Lamination  Tablet defects related to excipients Chipping; Sticking; Picking and Binding Tablet defects related to more than one factor Mottling Tablet defects related to machine Double impression Tablet Defects A perfect tablet should be free of any visual or functional flaws. The advancements and …

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Introduction to Drug Stability Stability studies ensure the maintenance of drug/product quality, safety, and efficacy throughout the shelf life. Stability studies are considered a prerequisite for the acceptance and approval of any pharmaceutical product. Stability testing is a routine procedure performed on drug substances and products. Stability studies are employed at various stages of product …

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Formulation of Hard Gelatin Capsule Hard Gelatin Capsules (HGC) Hard gelatin capsules are used for enclosing solid medicament or dry powders of drug substance. It is also known as dry filled capsule. They are less flexible and consist of cap and body. The cap is short while body is long. It is available in different …

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Pharmaceutical Excipients of Tablets Definition of Pharmaceutical Excipients “Any substance other than the active drug or prodrug that is included in the manufacturing process or is contained in a finished pharmaceutical dosage form.”Excipients are not inactive and have an impact on the manufacture, safety, and efficacy of the drug substance in the dosage form. Purposes …

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Importance of Rabbit and LAL Test Pyrogen Test in Parenterals What are Pyrogens? Pyrogens are fever-inducing substances usually derived from microorganisms, and when present systemically in sufficient quantity, may lead to severe signs of inflammation, shock, multiorgan failure, and sometimes even death in humans. Types of Pyrogen Tests? The rabbit pyrogen test (RPT) and the …

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Triple Roller Mill – Principle, Construction, Diagram, Working, Applications Triple Roller Mill is one of the equipment used for mixing purposes in various industries. It is also known as three roll mill. Principle of Triple Roller Mill A three roll mill or triple roller mill is a machine that uses shear force created by three …

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Double Cone Blender-Principle, Construction, Diagram, Working, Applications Mixing is one of the most common pharmaceutical operations. It is difficult to find a pharmaceutical product in which mixing is not done at one stage or the other during its manufacturing. Double Cone Blender is one of the commonly used equipment for mixing ingredients. Principle of Double …

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